Buy Nolvadex Online

Generic Nolvadex (tamoxifen) is a medication that can block the action of the female hormone estrogen, which causes certain types of breast cancer. It is used for breast cancer treatment and prevention. Also marketed as Apo-Tamox and Tamizam.

  • Name: Tamoxifen (Nolvadex)
  • Dosage: 10mg, 20mg
  • Pack: 30,60,90,180 pills
  • Price: from 1.03 $ Per Pill

Tamoxifen Cost for Sale

Tamoxifen nolvadex for sale is a medicinal preparation used for combination therapy of estrogen dependent forms of cancer in women. It was first opened in 1966 by a group of researchers from England. It was suggested that buy nolvadex online cheap can be used as a contraceptive in women. In 1971, the first studies of the possibility of using the drug for the treatment of breast cancer. By 1998, numerous studies have confirmed the use of tamoxifen for sale to treat cancer in women to improve the prognosis, save more lives. Estrogens in the body of a woman stimulate the growth of target cells. This is mainly the glandular tissue of the breast. Some forms of breast cancer require hormonal stimulation for their development. On its surface, cancer cells have receptors, to which estrogens join. Tamoxifen nolvadex for sale, like a broken key in the lock, connects to these receptors, preventing their activation by female sex hormones. And once the lock is blocked, there is no stimulating effect on cancer cells.Interestingly, buy nolvadex online over the counter is a selective antagonist of estrogen receptors. In other organs, for example in the uterus, he, on the contrary, enhances the effect of female sex hormones. There is best place to buy nolvadex online.

1 tablet of 10 mg contains: Active substance: tamoxifen citrate - 15.2 mg in terms of nolvadex buy - 10 mg.

Auxiliary substances: lactose monohydrate (sugar milk) - 62.0 mg, microcrystalline cellulose - 10.0 mg, corn starch - 7.3 mg, sodium carboxymethyl starch - 1.0 mg, povidone (polyvinylpyrrolidone) - 3.5 mg, magnesium Stearate 1.0 mg.

1 tablet of 20 mg contains: Active substance: buy nolvadex pct citrate - 30.4 mg in terms of buy nolvadex online - 20 mg. Auxiliary substances: lactose monohydrate (sugar milk) - 124.0 mg, microcrystalline cellulose - 20.0 mg, corn starch - 14.6 mg, sodium carboxymethyl starch - 2.0 mg, povidone nolvadex for sale (polyvinylpyrrolidone) - 7.0 mg, magnesium Stearate 2.0 mg.

Description

Tablets from white to white with a greyish-creamy hue of color, flat-cylindrical shape, with a facet on both sides and risk from one side. Pharmacotherapeutic group: antitumor agent - antiestrogen

Pharmacodynamics

Tamoxifen buy is a non-steroidal antiestrogenic agent that also has weak estrogenic properties. Its action is based on the ability to block estrogen receptors. Nolvadex for sale, as well as some of its metabolites, compete with estradiol for binding sites to the cytoplasmic estrogen receptors in the tissues of the mammary gland, uterus, vagina, anterior pituitary gland and tumors with a high estrogen receptor content. In contrast to the receptor complex of estrogen, the receptor complex of tamoxifen generic without prescription does not stimulate the synthesis of DNA in the nucleus, but inhibits cell division, which leads to regression of tumor cells as a result of their death.

Pharmacokinetics.

When taken orally, tamoxifen for sale is absorbed well. The maximum serum concentration is reached within 4 to 7 hours after taking a single dose. The equilibrium concentration of nolvadex buy in the blood serum is usually achieved after 3-4 weeks of admission. The connection with plasma proteins is 99%. Metabolized in the liver with the formation of several metabolites, the isozyme CYP2S9 participates in the metabolism. Excretion of buy nolvadex online from the body is biphasic with an initial half-life of 7 to 14 hours and with a subsequent slow terminal half-life for 7 days. It is excreted primarily through the intestine, mainly in the form of metabolites; A small amount - by the kidneys.

Indications for use

  • Adjuvant therapy for early breast cancer with estrogen-positive receptors.
  • Treatment of locally advanced or metastatic breast cancer with estrogen-positive receptors.
  • Breast cancer (including in men after castration).

Nolvadex for sale online can also be used in other solid tumors that are resistant to standard treatments, with overexpression of estrogen receptors.

Contraindications

Hypersensitivity to order nolvadex for sale and / or any other component of the drug; Pregnancy and lactation. Child age (data on effectiveness and safety in children are absent). With caution: eye diseases (including cataracts), expressed thrombophlebitis, thromboembolic disease (including in the history), hyperlipidemia, leukopenia, thrombocytopenia, hypercalcemia; Hereditary lactose intolerance, insufficiency of lactase or impaired absorption of glucose and galactose (the preparation contains lactose).

Dosing and Administration

Inside, not liquid, squeezed a small amount of liquid, in one session in the morning, or, dividing the necessary dose into two doses (morning and evening). The dosage regimen is usually set individually depending on the indications. The daily dose is 20-40 mg. As a standard dose, taking 20 mg of tamoxifen cost inside daily for a long time. When there are signs of progression of the disease, taking the drug is canceled.

Side effects

In the treatment of buy nolvadex online , the most frequent adverse reactions associated with its anti-estrogenic effect are manifested in the form of paroxysmal sensations of heat ("hot flashes"), vaginal bleeding or discharge, itching in the genital area, alopecia, pain in the area of ​​the lesion, ossalgia, . Less frequently or rarely, the following adverse reactions were observed: fluid retention, anorexia, nausea, vomiting, constipation, fatigue, depression, confusion, headache, dizziness, drowsiness, body temperature recurrence, skin rash (including occasional reports of erythema multiforme, syndrome Stevens-Johnson and bullous pemphigoid), visual impairment, including corneal changes, cataracts and retinopathy, retrobulbar neuritis. Interstitial pneumonitis was rarely observed. At the beginning of treatment, local exacerbation of the disease is possible - an increase in the size of soft tissue formations, sometimes accompanied by severe erythema of affected areas and adjacent areas, which usually occurs within 2 weeks. The likelihood of thrombophlebitis and thromboembolism may increase. Often leg cramps are noted.

Sometimes transient leukopenia and thrombocytopenia can occur, as well as an increase in the activity of "liver" enzymes, very rarely accompanied by more severe impairment of liver function, such as fatty liver, cholestasis and hepatitis. Rarely there was an increase in serum triglyceride levels in some cases combined with pancreatitis. In some patients with bone metastases at the beginning of treatment, hypercalcemia was observed. Tamoxifen causes amenorrhea or irregularity of menstrual periods purchase nolvadex over the counter citrate 20mg in premenopausal women, as well as the reversible occurrence of cystic ovarian tumors. With prolonged treatment with nolvadex for sale online, changes in the endometrium, including hyperplasia, polyps, development of uterine fibroids and in isolated cases - endometrial cancer, uterine sarcoma, can be observed.

Overdose

An acute overdose of buy tamoxifen online in humans was not observed. In case of overdose, neurotoxicity may develop (tremor, hyperreflexia, gait unsteadiness, dizziness). Specific antidote is not known. Treatment is symptomatic.

Interaction with other drugs

With the simultaneous administration of buy nolvadex online and cytostatics, the risk of thrombosis increases. There have been reports of nolvadex pills potentiating the anticoagulant effect of coumarin preparations (eg, warfarin). Drugs that reduce the excretion of calcium (eg, thiazide diuretics) may increase the risk of hypercalcemia. Joint use of tamoxifen and tegafur can promote the development of active chronic hepatitis and cirrhosis of the liver. The simultaneous use of nolvadex pct for sale cheap with other hormonal drugs (especially estrogen-containing contraceptives) leads to a weakening of the specific effects of both drugs. With the simultaneous use of nolvadex for sale over the counter and bromocriptine, there is an increase in the concentration cost of cheap tamoxifen and N-desmethyl tamoxifen in blood plasma. Tamoxifen should not be used concurrently with aromatase inhibitors (arimidex, letrozole).

special instructions

Women receiving buy nolvadex online should undergo regular gynecological examinations. When bloody discharge from the vagina or vaginal bleeding occurs, the drug should be discontinued. Tamoxifen can cause ovulation, which increases the risk of pregnancy, and therefore, women of reproductive age need to use reliable methods of contraception (non-hormonal) during treatment and within 3 months after the end of treatment. In patients with bone metastases, the concentration of calcium in serum should be determined periodically during the initial treatment period. In case of severe disorders (hypercalcemia), tamoxifen cost should be temporarily discontinued. When signs of thrombosis of the veins of the lower extremities (pain in the legs or their puffiness), pulmonary embolism (dyspnea), the drug should be stopped. During the period of therapy, it is necessary to periodically monitor the blood clotting parameters, the calcium content in the blood, the blood picture (leukocytes, platelets), the liver function indices, arterial pressure, and the oculist. In patients with hyperlipidemia, the concentration of cholesterol and triglycerides (TG) in serum should be monitored during treatment. During the treatment period, care must be taken when driving vehicles and engaging in potentially hazardous activities that require increased attention and speed of psychomotor reactions.

Form of issue

Tablets 10 mg and 20 mg. For 10, 30 tablets in a contour mesh box made of polyvinylchloride film and aluminum foil printed lacquered. For 10, 20, 30, 40, 50 or 100 tablets in cans of polymeric for medicines. One jar or 1, 2, 3, 4, 5 or 10 contour mesh packages together with the instruction for use are placed in a cardboard package (bundle). However, it is still believed that where to buy nolvadex online is a fairly mild drug. Probably, in the near future nolvadex pct for sale online will be used to prevent breast cancer in women who have a high risk of developing this disease.

A patent banning the production of nolvadex for sale cost by other pharmaceutical companies has expired in 2002. Currently, the drug is produced by many companies in Russia, too. The original preparation Nolvadex, Istubal, or Valodex, is manufactured by AstraZeneca in England. Consequently, tamoxifen cost in pharmacies in Moscow may be different.

Tamoxifen in bodybuilding

Officially, tamoxifen price for men has been used to treat breast cancer. Yes it is possible. Breast cancer in men is rare, but characterized by high mortality. The main consumers of tamoxifen among men are bodybuilders. Why do athletes take tamoxifen? The manufacturer instruction does not say anything about this. Moreover, despite the wide use of this drug, no serious studies have been done on how buy nolvadex online without prescription affects a healthy man. Side effects of the drug in healthy men can potentially cause harm to health. The use of drugs for purposes other than the manufacturer indications is at your own risk.

Tamoxifen, use in bodybuilding

It is no secret that professional sports require sacrifices. With respect to bodybuilding, this statement is true by 200%. It is impossible to achieve such indicators of muscle mass gain by training alone. In the 1970s, an anabolic steroids craze began. Anabolic steroids are substances that enhance anabolic processes in the body, mainly the synthesis of proteins and macromolecules. Active synthesis of proteins of muscle tissue leads to muscle hypertrophy, increase in physical strength. In medicine, anabolic steroids are used for dystrophic diseases, for recovery after severe injuries, burns, delay in physical development, and others. Athletes who use anabolic steroids sacrifice their health in the first place. The list of side effects of anabolic steroids is huge. Among them:

  • accelerated progression of atherosclerosis;
  • Iron-deficiency anemia;
  • peripheral edema;
  • dyspeptic phenomena;
  • impaired liver function, jaundice;
  • hypocoagulation, which manifests itself as a tendency to bleeding;
  • hepatonecrosis;
  • liver cancer;
  • Cholestatic hepatitis;
  • hypercalcemia;
  • in women: masculinization (acquiring features characteristic of men).

The use of steroids wears the heart muscle, no wonder many bodybuilders die in the prime of life from myocardial infarction. Normally, men have very small amounts of estrogens in their bodies. Most of the testosterone is converted to estrogens. This transformation takes place with the participation of the cytochrome p450 enzyme. When anabolic steroids are used, testosterone synthesis is abruptly induced, the body tries to eliminate excess hormone, converting testosterone to estradiol, the main female sex hormone. Excess of female sex hormone leads to the growth of the mammary gland in men or gynecomastia. There is a delay of water and sodium in the body, subcutaneous fat is laid down by the female type.

It is to prevent these side effects and buy nolvadex online otc is used. By binding receptors to estrogen in breast cells, tamoxifen cost prevents gynecomastia and other side effects associated with an increase in the level of estrogens.

Tamoxifen, analogues of the drug, dosage

Basically nolvadex price is an imported drug. In Russia it is produced by the pharmaceutical company Ozone. The dosage of the drug depends on the manufacturer, in the market there are tablets tamoxifen 20, 30, 40 mg. In general, the most common is tamoxifen 20 mg. Pharmaceutical firms offering tamoxifen, manufacturers:

  • 1. Active ingredient: buy tamoxifen citrate 20mg. Country manufacturer of nolvadex for sale without prescription - Austria. The manufacturer of the drug where to where can i buy nolvadex online - Ebwe. Tamoxifen Ebeve: in the presence of the manufacturer there are tablets with a dosage of 10, 20, 30, 40 mg.
  • 2. Active ingredient: nolvadex pct for sale citrate. Country manufacturer of tamoxifen - Finland. The manufacturer of tamoxifen is Orion Corporation. Dosage of 10 and 20 mg.
  • 3. Active ingredient: tamoxifen citrate for sale. The country of the manufacturer of the drug is Germany. The manufacturer of the drug tamoxifen - Hexal AG. Dosage of 10, 20, 30, 40 mg.
  • 4. Active ingredient: tamoxifen price citrate. Country of origin - Russia. The company is manufacturer - Ozon Pharmaceutical Company. Dosage of 10 and 20 mg.

There are many different manufacturers of tamoxifen cost in the world. The presence of medications in other pharmacies in Moscow should not embarrass you. After the termination of the patent for exclusive manufacture of a preparation many firms start to let out analogues, especially if the medicine well works. Compliance with the original drug is checked in the laboratory.

Other Medication

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