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Tamoxifen is an estrogen antagonist; used to treat breast cancer. Combined with hormone receptors present on tumor cells, it inhibits the action of estrogens. Side effects are rare; these include: flushing, soreness of the tumor and hypercalcemia. Research is currently being conducted on the possibility of taking tamoxifen by women who are at risk of developing breast cancer in them to prevent its development. You can buy nolvadex online without prescription in our online pharmacy. Just click link below:

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Indications

It is used in the complex treatment of breast cancer (including those that have arisen in men, including those accompanied by the formation of metastases), in the postmenopausal period, with oncological changes of the endometrium, with oncological lesions of the lymph nodes, and also in the case of diagnosed anovulatory infertility.

–°ontraindications

It is not prescribed if the patient is hypersensitive to the components of the drug. It also does not apply if the patient has been diagnosed with a severe form of diseases such as thrombocytopenia, leukopenia, as well as hypercalcemia.

Use during pregnancy and lactation

Do not appoint either during pregnancy or during lactation.

Dosage and administration

Accept inside, on the individual scheme of the treatment approved by the attending oncologist. Usually, for breast cancer, they take from 20 to 40 milligrams once a day, or by dividing the daily dose into 2 doses. In the case of treatment of endometrial cancer of the uterus, the dose is slightly higher and starts from 30 milligrams per dose.

Anovulatory infertility is treated with this drug at a dosage of 10 mg twice a day for the first four days, starting from the second day of the menstrual cycle. In the next four days, the dose may increase to 20, and then to 40 mg. The regimen does not change - twice a day.

Side effects

The use of Tamoxifen may cause side effects, primarily from the gastrointestinal tract. In particular, an upset stomach (constipation, diarrhea), nausea, vomiting. There may be an allergic reaction from the skin, such as itching, hives, skin rash.

The amount of calcium in the blood may increase, hypercalcemia may occur. Also rarely occurs the phenomenon of thrombocytopenia, that is, a decrease in the number of platelets in the blood. With the appearance of uterine bleeding, even moderate (ie, with metrorrhagia), the dosage should be reduced.

Cases of vascular occlusion by blood clots (thrombosis) have been noted. Therapy when using large doses for a long time can cause changes in the eye retina.

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